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To measure the effect of the paramagnetic label, 1 H, 15 N and 1 H, 13 C HSQC spectra with long inter-scan delays (3 s) of 100 M 13 C/ 15 N-labeled p53 TAD2 in presence of one stoichiometric equivalent paramagnetically labeled FOXO4 FH were recorded before and after addition of 5 mM ascorbic acid

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While DCE-MRI is an established contrast-enhancement technique with routine clinical use, an emerging contrast-enhanced technique with promising clinical application worth mentioning, is chemical exchange saturation transfer (CEST)

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It also downregulated pro-inflammatory signaling through inhibition of NF-B, COX-2, and TRPV1, suggesting a dual antioxidant and anti-inflammatory action that supported both mucosal integrity and epithelial regeneration